Common causes of sore throat
Sore throat (pharyngitis) has many causes, but the picture is usually one of these:
Viral infections
By far the most common cause — around 80–85% of sore throats. Common viruses include rhinovirus (common cold), adenovirus, influenza, COVID-19, parainfluenza, enterovirus, and Epstein-Barr virus (glandular fever). Viral sore throats don’t benefit from antibiotics — they need symptomatic relief and time.
Bacterial infections
Around 5–15% of sore throats are bacterial, most commonly Group A Streptococcus ("strep throat"). Bacterial throat infections benefit from antibiotic treatment to reduce duration, prevent complications, and reduce transmission. Distinguishing bacterial from viral on clinical examination alone isn’t perfectly reliable, which is why we use a structured scoring system (FeverPAIN or Centor) and may use a throat swab.
Glandular fever (infectious mononucleosis)
Caused by Epstein-Barr virus. Particularly common in teenagers and young adults. Causes severe, prolonged sore throat with tonsil enlargement, fever, swollen lymph nodes, and profound fatigue. Often misdiagnosed initially as bacterial. Blood test confirms.
Non-infective causes
- Reflux (acid coming up from stomach causes chronic throat irritation)
- Allergies (postnasal drip)
- Air pollution, smoking
- Voice overuse
- Dry air
- Side effects of certain medications
Less common but important
- Peritonsillar abscess ("quinsy") — complication of tonsillitis
- Epiglottitis — rare but life-threatening airway infection
- Throat cancer (rare; usually presents with persistent hoarseness, pain, or swelling, especially in older smokers/drinkers)
Telling viral from bacterial
Two validated scoring systems help estimate the likelihood of bacterial (specifically streptococcal) infection:
FeverPAIN score (UK NICE-recommended)
- Fever (during previous 24h)
- Purulent tonsils (pus)
- Attended within 3 days of onset
- Inflamed tonsils (severely)
- No cough or coryza (cold symptoms)
Each item scores 1 point. Higher scores indicate higher likelihood of bacterial infection.
Centor score
Similar tool, scoring tonsillar exudate, tender neck lymph nodes, absence of cough, and fever.
These scores guide whether antibiotics are appropriate and/or whether a throat swab is worth doing. Low scores: viral very likely, no antibiotics. High scores: bacterial more likely, antibiotics often justified.
When sore throat is urgent
Seek urgent medical care
Some symptoms with sore throat are emergencies. Call 999 or go to A&E if:
• Stridor — high-pitched harsh sound when breathing in
• Drooling and inability to swallow saliva
• Severe difficulty breathing or noisy breathing
• Cannot open mouth properly (trismus)
• Muffled voice ("hot potato" voice)
• Severe one-sided throat swelling
• Confusion or extreme drowsiness
These can indicate epiglottitis (rare but life-threatening), peritonsillar abscess, or severe airway compromise. Don’t wait.
How we assess at MHW
1. History
Duration, fever, swallowing difficulty, breathing difficulty, voice change, recent contacts (school, family), travel history, smoking, alcohol, immunisation status, previous tonsillitis pattern, other symptoms.
2. Examination
- Throat examination — tonsil size, redness, exudate, ulceration, asymmetry
- Neck examination — lymph node enlargement
- Ear examination (otitis media is sometimes mistaken for sore throat or co-exists)
- Temperature
- Other vital signs if unwell
3. Scoring
FeverPAIN or Centor score to estimate likelihood of bacterial infection and guide treatment.
4. Throat swab if appropriate
For intermediate scores, or where treatment decisions are difficult, a swab from the tonsils sent for laboratory culture (or rapid antigen test) identifies bacterial causes. Available same-day at MHW. Results from culture take 24–72 hours; rapid antigen testing gives same-visit results for strep.
5. Blood tests where indicated
- Glandular fever screen (Paul-Bunnell / monospot, plus EBV serology if needed)
- Full blood count (if severe or atypical illness)
- CRP (inflammatory marker)
6. Plan
Either symptomatic management alone, antibiotics if bacterial cause confirmed/likely, or escalation (referral) for severe or atypical presentations.
Treatment options
Self-care (for any sore throat)
- Rest, fluids
- Paracetamol or ibuprofen for pain and fever
- Salt water gargles
- Honey and lemon drinks (over 1 year of age)
- Throat lozenges
- Cool drinks, ice lollies for severe pain
Antibiotics if indicated
For confirmed or likely bacterial infection (high FeverPAIN/Centor score, positive swab, or specific clinical features), a short course of antibiotics typically reduces symptom duration by about a day and prevents the small risk of complications (rheumatic fever, kidney problems). We follow NICE NG84 for prescribing decisions and inform you of the rationale. UK law prevents naming specific medications on this website.
For glandular fever
No antibiotics needed (and a specific class of antibiotic should be avoided as it commonly causes a rash in EBV infection). Rest, fluids, time. Avoid contact sports for several weeks because of risk of splenic injury.
Hospital referral
For peritonsillar abscess, suspected epiglottitis, airway concerns, or severe systemic illness, we arrange urgent ENT or A&E referral as appropriate.
Recurrent sore throat
If you’re getting frequent severe sore throats — especially with confirmed tonsillitis — tonsillectomy may be worth considering. The threshold (per ENT UK / SIGN guidance):
- 7 or more documented episodes in 1 year, OR
- 5 or more in each of 2 years, OR
- 3 or more in each of 3 years
With each episode severe enough to need a doctor and time off work/school. We can refer for private ENT assessment and tonsillectomy if appropriate.
When to see us
Consider same-day booking if:
- Severe sore throat with high fever
- Difficulty swallowing fluids
- One-sided throat pain or swelling
- Sore throat lasting more than a week without improvement
- Recurrent tonsillitis (3+ episodes in a year)
- Sore throat in someone immunocompromised
- Significant systemic symptoms (fever, severe fatigue, neck swelling)
Call 999 or go to A&E for stridor, drooling, severe breathing difficulty, or extreme one-sided swelling (see red flags above).
Frequently asked questions
Will I definitely get antibiotics?
No — not unless they’re indicated. Around 85% of sore throats are viral and antibiotics don’t help. Inappropriate antibiotic use contributes to resistance. We use validated scoring and swabs to make the right decision.
How quickly will I know if I need antibiotics?
For most cases, we make the decision at the appointment based on examination and scoring. Throat swab results take 24–72 hours but rarely change immediate management for a clear clinical picture.
Could it be COVID?
Yes — COVID is now a common cause of sore throat. We can test on site (PCR or rapid antigen) if you wish.
What about glandular fever?
If symptoms are severe, prolonged, or you’re a teenager/young adult with marked fatigue and lymph node swelling, we test specifically for glandular fever. Blood tests take 1–3 days.
When should I worry about strep complications?
The rare complications of streptococcal throat infection (rheumatic fever, post-streptococcal kidney inflammation, scarlet fever) are reasons to treat confirmed bacterial throat infections. These are rare in the UK but worth being aware of, particularly with severe presentations.
How much does the appointment cost?
Current prices are on our Fees page. Throat swab and blood tests are additional and quoted before being done.
Can children come?
Yes — we see children from any age. Children must attend with a parent or guardian. For very young children with severe symptoms, A&E or our urgent care service may be appropriate.
What if my sore throat keeps coming back?
Worth a fuller assessment — checking for underlying cause (reflux, allergies, immune issues), pattern of recurrence, and whether tonsillectomy might help. Book a longer initial consultation rather than another same-day appointment.